Differin Gel is an over-the-counter acne treatment that contains 0.1% adapalene, a retinoid that was once available only by prescription. This transition to OTC availability has made it more affordable for individuals dealing with mild to moderate acne. Adapalene is its primary active ingredient, works by regulating skin cell turnover which helps to prevent clogged pores and is one of the root causes of acne. Its anti-inflammatory properties also help reduce redness and swelling associated with acne breakouts. Differin Gel is also recommended by Dr. Dina Strachan, a board-certified dermatologist and assistant clinical professor at New York University. Since it’s suitable for all forms of acne, Differin Gel is considered a reliable and practical option for many people struggling with acne, offering clinical strength without the need for any prescription.

Tazorac is a prescription-strength topical medication used primarily to treat acne and psoriasis. Its active ingredient is tazarotene, a type of retinoid similar to adapalene which helps regulate skin cell turnover. For some severe types of acne, such as cystic acne or acne on other parts of the body, Tazorac cream may be recommended. Pregnancy should not be the time to utilize it. Plus, when taking this product, be sure to wear sunscreen frequently because it can sometimes cause some sensitivity to light and sunlight. Tazorac is available in different strengths (usually 0.05% and 0.1%) and comes in both cream and gel forms. It is typically applied once daily, preferably in the evening, to clean, dry skin.

INNBeauty Project Pimple Paste is a targeted, spot-treatment product designed to quickly address pimples and acne breakouts. It is a clean, vegan, and cruelty free formulation that combines several powerful ingredients to reduce inflammation, dry out blemishes and prevent future breakouts. Sulfur-based products reduce skin inflammation due to their antibacterial and anti-inflammatory qualities. This paste which is on the list of best acne creams in Pakistan contains active ingredients that are great at stopping breakouts including azelaic acid, sulfur and tea tree unlike toothpaste which contains harsh ingredients. For best results, apply the Pimple Paste as an overnight spot treatment. This method which is not recommended for all-over treatment allows the paste’s active ingredients to work effectively.

Tretinoin also known as all-trans retinoic acid (ATRA) is a prescription-strength topical cream or gel derived from vitamin A. It is one of the best acne treatments in Pakistan, speeding up skin cell turnover by making cells divide and die faster, allowing new ones to surface. Besides treating acne, tretinoin improves wrinkles and fine lines, unclogs pores, and prevents them from clogging again. But it should only be used under the guidance of a dermatologist, so be sure to consult a trusted doctor before starting treatment with this effective acne cream. It is available in topical and oral forms.

It is widely used to cure chronic acne in Pakistan. Altreno is a high-end option that contains tretinoin, a retinoid commonly prescribed to treat acne. Unlike the other tretinoins and retinoids, it is present in the form of lotion instead of cream or gel.  It targets breakouts by moisturizing the skin. Topical retinoids are a foundational treatment for acne. They work like pipe cleaners by keeping your pores open. Retinoids are the best acne creams in Pakistan. They prevent the cells from sticking together and blocking the pores while trapping oil within them. These also help a lot in enhancing cell turnover and even skin texture and skin tone. 

VINCE Anti Acne Cream is an extremely effective combination of highly potent antimicrobials and antioxidants that help to kill acne causing bacteria, calm redness and lighten acne marks. High concentrations of potassium Azeloyl Diglycinate and capryloyl Salicylic Acid not only fade dark spots and brighten dull areas of your skin but also balance oil production and stimulate cell renewal on your skin. It helps to refine and tighten skin pores and gives you healthy, younger looking spotless skin. For best results, it is advisable to consult a dermatologist especially if you have sensitive skin or are dealing with severe acne​.